DIY Genetic Engineering
This site has a story of how a software guy builds a glowing yeast strain. He used readily available equipment and mailorder chemicals. Given it is specialized equipmewnt but it was available on ebay for about 5g's. He had no prior history in it and was taught how to do it. In reading the article it really isn't hard. Genetic engineering apoarently follows a growth curve greater than Moores Law. Basically the faster it gets, the faster it gets.
He did it himself, while being told how to by a geneticist. Apparently, the scaling up to small pox is a a bit trickier but can still be done. Also apparently there are mailorder houses that sell gene sequences. I did a quick search on ebay for gene sequencer and found that the hardware to make this stuff isn't expensive. There was a Synthesizer with a BuyItNow of 250. With free shipping to boot. Gene sequences are available for download so you have a blueprint of what you want to make.
Am I scaring you yet? DNA is the building block of viruses and life. With this equipment you could make your very own customized version of AIDS or Anthrax. Or you could make a dog with 5 legs. As frightening as this could be I can't help but wonder what this means in the long run. With the maker mentality and the availability of equipment backyard gene doping could become a reality. On the flip side, the faster we can code dna and rna, the faster we can eliminate most if not all viral diseases like aids.
Semms like a we're in the beginning of a William Gibson World.